Dameon Pierce got loose on Sunday in Nashville.
The Texans running back took a handoff at Houston's own 8-yard line, burst through the right side of the line, and raced away from the Tennessee Titans for a 92-yard touchdown run at Nissan Stadium.
The point-after try was unsuccessful, and Houston held a 13-0 lead with 13:55 remaining in the second quarter.
For Pierce, it was the longest run of his career, and it pushed him over 200 yards for the season.
The third-year running back now has two touchdowns 2024, with other coming on a 54-yard jaunt in the win at New England.
Pierce's scoring run was the only play of the Texans' third possession of the game, and it lasted 12 seconds.
