Whitney Mercilus, Garrett Graham, and rookie Xavier Su'a-Filo were ruled out of Sunday's game in Indianapolis after missing practice this week.
Mercilus suffered a back issue in the Texans 27-13 win over Jacksonville. Graham will miss a second-consecutive game with a lingering ankle injury.
Andre Johnson is currently undergoing the league's concussion protocol and is listed as questionable in Week 15. Read more on Johnson here.
HOUSTON TEXANS
Friday (12/12/14)
OUT
TE Garrett Graham (DNP) Ankle
OLB Whitney Mercilus (DNP) Back
G Xavier Su'a-Filo (DNP) Back
QUESTIONABLE
WR Andre Johnson (Limited) Concussion
PROBABLE
T Tyson Clabo (Full) Foot
ILB Brian Cushing (Full) Back/Ankle
ILB Akeem Dent (Full) Neck
RB Arian Foster (Full) Groin
CB Kareem Jackson (Full) Knee
CB Johnathan Joseph (Full) Knee/Achilles
S Danieal Manning (Full) Hamstring
ILB Jeff Tarpinian (Full) Knee
**NOTE - DE Tim Jamison was placed on injured reserve Friday afternoon and taken off the game status report
INDIANAPOLIS COLTS
Friday (12/12/14)
OUT
G Joe Reitz (DNP) Ankle
G Hugh Thornton (DNP Knee
PROBABLE
S Mike Adams (Full) Back
S Sergio Brown (Full) Illness
CB Darius Butler (Full) Illness
CB Vontae Davis (Full) Concussion
WR T.Y. Hilton (Full) Rest
LB D'Qwell Jackson (Full) Ribs
S Laron Landry (Full) Illness
T Xavier Nixon (Full) Foot
LB Andy Studebacker (Full) Hamstring
LB Erik Walden (Full) Knee
WR Reggie Wayne (Full) Rest