Fresh off a J.J. Watt pick-6, the Texans defense doubled down and got a second turnover.
Trailing 7-6 with just under 5 minutes remaining in the opening quarter, Tyrell Adams and Ross Blacklock stripped the ball loose from Detroit's James Williams, and cornerback Bradley Roby pounced on it at the Lions 30-yard line.
On the Lions' previous offensive play, Watt intercepted a Matt Stafford pass and returned it 19 yards for a touchdown.
After the Roby fumble recovery, Deshaun Watson and the offense wasted little time in finding the end zone. He found Duke Johnson on the left side for a pickup of 14 yards, then went back to Johnson in the end zone on the next play. The pass was incomplete, but the Lions were called for pass interference. On the ensuing play, a 1st-and-Goal at the Lions' 1-yard line, C.J. Prosise was pushed back for a loss of a yard.
Then Watson tossed a 2-yard strike to Prosise for the score.
The Ka'imi Fairbairn extra point put the Texans on top, 13-7 with 2:58 remaining in the opening quarter.